To set up an automated online store for passive income, choose a profitable niche and products, then build your store on platforms like Shopify or WooCommerce. Use automation tools for dropshipping, payment processing, marketing (email campaigns, ads, social media), and customer support (chatbots). Integrate services like Oberlo or Spocket for product sourcing, and set up analytics to track performance. Outsource tasks like customer service or content creation if needed. This system reduces manual effort, allowing you to generate passive income with minimal day-to-day involvement.